Prime® may be used during tank cycling to alleviate ammonia/nitrite toxicity. It contains a binder which renders ammonia, nitrite, and nitrate non-toxic, allowing the biofilter to more efficiently remove them. It will also detoxify any heavy metals found in the tap water at typical concentration levels. Use at start-up and whenever adding or replacing water. When transporting or quarantining fish, use Seachem StressGuard™. When adding new fish, use Stability®. Both are ideal for use with Prime®.